The 7-th International Scientific Teleconference "New Technology in Medicine - 2010"

Bulletin of the International Scientific Surgical Association, 2010, Vol. 5, N. 1

Russian version

The antibioticograms of 63 hospital strains of Klebsiella pneumoniae and possibility of their inactivation by means of photodynamic influence were studied. As a photosensitizer we used solutions of methylene-blue (МB) in concentrations of 0,001 %, 0,005 %, 0,01 % and 0,05 %, the installation FDU-1 with radiation in a spectral range of 600-660 nanometers, power of 5 Wt and power density of 250-500 mWt/cm2 served as a source of light (red) radiation.

It was determined, that the antimicrobic activity of the PhDT depended both on MB concentration and on the radiation exposition. The most expressed effect was registered at use of MB solution of 0,05 % and exposition of 3-10 minutes.

Thus, antimicrobic PhDT is characterized by expressed inhibiting activity in relation to polyresistant strains of K. pneumoniae that proves the perspectives of its application at treatment of nosocomial pyoinflammatory processes.

The relevance of problem. The hyperglycemic ketoacidosis coma is the serious complication of the insular diabetes. This is an one of the compound problems in the clinical medicine. It is demanding the special attention, because it has a grave process and a high lethality.

The matter of research: the diabetes afflicted persons with a complicated by hyperglycemic ketoacidosis coma.

Object of the research: a working out and a substantiation of the differentiated (varied) method to estimation of gravity the condition of patients and a choice of tactics the pathogenetically well-founded infusional programs in a complex of an intensive therapy diabetes afflicted persons with a complicated by hyperglycemic ketoacidosis coma.

The field of application: anesthesiology, resuscitation, an intensive care, endocrinology.

The purpose of this research is creation of information system for oncologists and doctors-radiologists, which allows planning a course of radiation therapy with application of specially developed mathematical methods and models.

In paper the model of a pneumoconiosis on rats is featured at intratracheal support of a coal-rock dust. Matching with telltale bunch institutes for model animals morphological variations similar at a pneumoconiosis. For model animals the raise of levels of autoantibodies to antigens of lungs, kidney, a thymus gland, joints, n-DNA and d-DNA is determined.

The effective method of the prevention of the recurrence of pain symptoms in surgical interventions on lumbar intervertebral discs was developed and put into practice.

The essence of the method consists in the following: the cavity, formed after removal of the pathological altered intervertebral disc, and the remainder of pulposis kernel, are irrigated by the Papain enzyme.

The proposed method is used in treatment of 92 patients. The analysis of treatment results showed the regress of clinical symptoms, including pain syndrome, in 98,91% of patients. The control MRI of lumbar spine of 29 patients showed no signs of herniated underwent surgery intervertebral disc relapse, in terms of 1 to 6 weeks after the surgery, as well as in late postoperative period (up to 18 months).

An experience of laparoscopic surgery in patients with previously deferred laparotomy. The possibility of the safe installation of the first trocar during laparoscopic operations to eliminate the possibility of internal injuries in patients with previously replaced laparotomy.

The method of laparoscopic cholecystectomy of two approaches for chronic calculous cholecystitis

A method for enhancing biological suture materials for gepatorafii. The method can be used in the manufacture of surgical suture and immediately before surgery on the liver.

18 patients with the symptomatic epilepsy were studied (12 men even 6 women). The cranio - cerebral injury was the etiological factor more frequently, without of the sex differences. Typical epileptic phenomens on the electroencephalography in patients with symptomatic epilepsy were fixed relatively rarely, in spite of conducting functional tests. The mono-therapy predominated in the treatment, women obtained valproats of more frequently, than men (р<0,05). The quality of life is below (р<0,05) in women. Differences it was not observed during the estimation of the cognitive scales and emotional status.

Aim: Identify additional microbiological criteria, conductive to the development of severe, progressive pulmonary tuberculosis.

We identified of primary multidrug resistance and the spectrum of genetic mutations of DNA M. tuberculosis clinical isolates in sputum from 48 patients with different types of flow of tuberculosis. In all patients, determination of drug sensitivity to rifampicin and isoniazid was carried out on biological microchips. Technology research, a set of reagents and equipment were developed in Engelhardt Institute of Molecular Biology Russian Academy of Sciences. In patients with severe progressive course of tuberculous process in comparison with in patients with favorable course of TB significantly more frequent to occur following mutations: in a gene rpo B (ser531) and in the gene kat G (ser 315), indicating a high level of primary multidrug resistance in these patients.

The MAO inhibiting activity was found for products of aminolis of 2-amino-5-benziliden-1,3-thiazol-4 (5Н)-ones in secondary amines. Except of predicted transamination it was also found that the recyclisation 2-amino-5-benziliden-1,3-thiazol-4 (5Н)-ones occurs as the result of aminolis. The scheme of the recyclisation is presented. The described rearrangement has allowed us to obtain new (5Z)-5-benziliden-2-morfolin-4-il-1,5-dihydro-4Н-imidazol-4-ones, containing the substitute in p-position of a benzene ring.

Saratov state research institute of rural hygiene, Saratov, Russia

The effectiveness of methods of radiodiagnosis of obstructive jaundice in the verification of the residents of the North (Komi Republic) are analysed in the article. The analysis showed the frequency of applied methods, as well as informative of each method depending on the objectives of the diagnostic procedure.

Objective value of the bloodlimfocirculation in tissue and organs dur-ing obliterative diseases of arteries is the actual problem. Especially it is important among war veterans suffered from battle injurious and stress. Registration of the microcirculation allow to work out optimal tactics of the treatment, evaluate its effection, define rehabilitation potentials and prognosis.

On the base of the system-functional ideas of P.K. Anokhin, into t.ch. about the efferent synthesis, and theory of N.A. Bernstein about the hierarchical mechanism of control of motions the statics of posture is examined in the context of the integral functional system of organism taking into account sensory syntheses specific for each level of control.

The work contains the results of investigation vestibular myogenic evoked potentials in patients with vestibulo-ataxic syndromes of different etiology. The present study demonstrates that inhibition of vestibulo-spinal reflex with P13 latency increase is most characteristic for demyelinating and traumatic brain diseases. P13 latency increase is not pathognomonic for any disease of nervous system accompanied with vestibulo-ataxic syndrome, but it is indicative of conduction delay in vestibulo-spinal tracts

Method of transresonans very short wave diagnostic based on effect of absorption radiation by water in tissue of human eye. Developing modification this method for vitreous body of eye. Antenna-applicator attached on anterior segment of eye. Clinical-experimental research to show ability registration of hydratation of vitreous body of eye. Presented results of normal level of hydratation of vitreous body in different groups of patients (age-related correlation). This method can be use in clinical practice for diagnostic condition of vitreous body of human eye.

There was a check up and curing of 323 patients with heterospecific empyema, 208 patients were cured by combined method with using thoracoscopy and “Gejser” device. That method lets to reduce the number of postoperative complications and the time of being in a day and night clinic.

The paper gives discription of exploration and curing 38 childrens from hepatophyma, 16 childrens were operated using minimally invasive surgery method by ultrasound investigation and 22 childrens were operated by accessible method using technic, that was created in clinic. It allowed decreasing the time of curing in a day and night clinic and realizing the individual approach to every patient.

Objectives. Reduction of the traumatic surgery treatment for fractures in lower thoracic and lumbar spine.

Materials and methods. The outcomes after minimally invasive anterior interbody fusion alone and in combination with percutaneous pedicle screw fixation for communited vertebral fractures in lower thoracic and lumbar spine were designed and successfully applying in 56 clinical cases (37 pacients). This approach can be realized by special instruments set. Stabilization of the spine was achieved with percutaneous pedicle screw fixation in 19 cases (BI – BII AO/ASIF). The anterior stabilization TiNi implant`s was complemented by system placed to anterior surfaces of vertebras bodies in 11 cases (AII – AIII). The authors present a comparative analysis of this method with classics anterior interbody fusion (n =23) and pedicle screw fixation (n=13).

Results. The outcomes surgical treatment were followed for 1 to 2 years (31 pacients). A minimally invasive anterior fusion alone and in combination with percutaneous pedicle screw fixation resulted in good results in 93.5 % of clinical cases (n=29), satisfactory in 6.5 % (n=2).

The purpose of our research was increase of efficiency of diagnostics and treatment of strictly sinusitis. Patients received besides traditional therapy of a sharp sinusitis a course of therapy with application of a low-frequency variable electrostatic field. For this purpose the device «Hivamat - 200» was used. Its work is based on action of a variable low-frequency electrostatic field.

In our days thoracoscopic method in diagnostics and treatment get the most expansion in modern thoracic surgery. The local contra-indications are strong commissural process and pleural obliteration. Complex method of pre-surgical prediction of commissural intensity in pleural cavity is needed for the improvement rendering of medical help and operational safety. The surgical classification and radiological measures get involved. The possibilities of radiological method in diagnostics pleural commissural process were studied. Because of subjectivism and necessity of high-tech equipment radiology is not sufficient method in this case. This subject is needed to further study.

A special device has been proposed in order to place the body of the patient reliably in need of operating intervention in lateral position.